Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641477 | 0.88 | CRBN (0.56) | CRBNDDB1POLB | |
| SCHEMBL30643581 | 0.88 | CRBN (0.56) | CRBNDDB1POLB | |
| SCHEMBL26641065 | 0.85 | CRBN (0.54) | CRBNDDB1POLB | |
| SCHEMBL25822350 | 0.79 | CRBN (0.65) | CRBNDDB1POLB | |
| SCHEMBL30643604 | 0.79 | CRBN (0.54) | CRBNDDB1POLB | |
| SCHEMBL30830925 | 0.79 | CRBN (0.58) | CRBNDDB1 | |
| SCHEMBL26641131 | 0.79 | CRBN (0.54) | CRBNDDB1POLB | |
| SCHEMBL24548362 | 0.78 | CRBN (0.63) | CRBNDDB1POLB | |
| SCHEMBL30643605 | 0.77 | DDB1 (0.65) | CRBNDDB1POLB | |
| SCHEMBL26641296 | 0.77 | DDB1 (0.65) | CRBNDDB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |