SCHEMBL306439

SCHEMBL306439

Oc1ccc(C(F)(c2ccc(O)cc2)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.58
ESR2 Q92731 11/20 0.58
KIF11 P52732 1/20 0.50
CYP3A4 P08684 3/20 0.44
LMNA P02545 2/20 0.44
TYR P14679 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
AR P10275 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679251 0.93 ESR1 (0.56) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL3686224 0.91 ESR1 (0.54) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL3686212 0.91 ESR1 (0.54) ESR1ESR2KIF11CYP3A4LMNA
Perflutren SCHEMBL8603202 0.81 ESR1 (0.57) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL5068336 0.80 ESR1 (0.58) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL7104727 0.79 ESR1 (0.50) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL1353159 0.78 ESR1 (0.56) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL27946251 0.78 ESR1 (0.77) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL28423412 0.77 KCNN4 (0.38) ESR1ESR2CYP3A4MEN1NPC1
SCHEMBL8613201 0.76 ESR1 (0.54) ESR1ESR2KIF11CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119742538-A Composite diaphragm based on solid electrolyte coating and preparation method thereof 宁波长阳科技股份有限公司 2025-04-01 CN claimed
CN-116144029-B Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华新材料科技股份有限公司 2025-03-18 CN claimed
CN-119192557-A Fluorine-containing polyarylether containing crosslinked network structure, and preparation method and application thereof 山东星顺新材料有限公司 2024-12-27 CN claimed
WO-2024064107-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS THE CHEMOURS COMPANY FC, LLC (US) 2024-03-28 WO claimed
CN-116144029-A Organosilicon leveling agent, preparation method thereof, black matrix photosensitive resin composition, color filter and liquid crystal display device 阜阳欣奕华材料科技有限公司 2023-05-23 CN claimed
EP-3938478-B1 USE OF OILS COMPRISING NON-NEUROTOXIC ANTI-WEAR ADDITIVES NYCO (FR) 2023-01-18 EP claimed
CN-110756060-B High-side-chain-density fluorine-containing polyarylether anion exchange membrane and preparation method thereof 浙江工业大学 2022-08-30 CN claimed
CN-113683805-B Preparation method of cross-linked imidazole functionalized polyether sulphone anion exchange membrane containing benzimidazole structure 浙江工业大学 2022-06-21 CN claimed
CN-111821870-B Solvent-resistant composite nanofiltration membrane and preparation method thereof 湖北瑞滤膜科技有限公司 2022-03-25 CN claimed
EP-3938478-A1 USE OF OILS COMPRISING NON-NEUROTOXIC ANTI-WEAR ADDITIVES NYCO (FR) 2022-01-19 EP claimed
US-20140000751-A1 POLYESTER CO-PHOSPHONATES DOSKOCIL MANUFACTURING COMPANY, INC. 2014-01-02 US claimed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-6583255-B1 Polyester oligomer THE BOEING COMPANY 2003-06-24 US claimed
US-5756645-A Multidimensional polyesters THE BOEING COMPANY (US) 1998-05-26 US claimed
US-5739256-A Method for making multidimensional polyester oligomers THE BOEING COMPANY (US) 1998-04-14 US claimed
EP-0279462-B1 4,4'-(PERFLUOROISOPROPYLIDENE)DICYCLOHEXANOL, DERIVATIVE THEREOF AND PROCESS FOR PREPARING THE SAME DAIKIN INDUSTRIES, LIMITED (JP) 1992-05-13 EP claimed
US-4978808-A NITRATION OF 2,2-BIS/P-HYDROXYPHENYL/HEXAFLUOROPROPANE WITH NITRIC ACID IN A LOW FATTY ACID CENTRAL GLASS COMPANY, LIMITED (JP) 1990-12-18 US claimed
US-4871475-A Polysulfone and polyethersulfone oligomers THE BOEING COMPANY (US) 1989-10-03 US claimed
US-4851501-A Polyethersulfone prepregs, composites, and blends THE BOEING COMPANY (US) 1989-07-25 US claimed
US-4788327-A CURABLE RESINS AND CROSSLINKING AGENTS DAIKEN INDUSTRIES, LTD. (JP) 1988-11-29 US claimed