Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 11/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623842 | 0.86 | GRIN2D (0.48) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1781248 | 0.85 | MAP4K4 (0.53) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20491766 | 0.85 | AKR1C3 (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20456794 | 0.85 | AKR1C3 (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20456700 | 0.85 | AKR1C3 (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21812428 | 0.85 | AKR1C3 (0.53) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23253058 | 0.84 | SOS1 (0.46) | SOS1LRRK2 | |
| SCHEMBL20456847 | 0.84 | SOS1 (0.42) | SOS1LRRK2MAP4K4 | |
| SCHEMBL20456845 | 0.84 | SOS1 (0.42) | SOS1LRRK2MAP4K4 | |
| SCHEMBL20469097 | 0.84 | SOS1 (0.46) | SOS1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003755-A | Pyrazolopyridazinone derivatives, compositions and uses thereof | 北京伯汇生物技术有限公司 | 2023-11-07 | — | — | CN | disclosed |