Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26597500 | 1.00 | MAPT (0.42) | MAPTNPSR1CNR1GPR35GPR55 | |
| SCHEMBL20510119 | 0.88 | MAPT (0.46) | MAPTNPSR1CNR1GPR35GPR55 | |
| SCHEMBL21465702 | 0.87 | KMT2A (0.45) | MAPTNPSR1CNR1GPR35GPR55 | |
| SCHEMBL26597490 | 0.87 | NPSR1 (0.45) | MAPTNPSR1KMT2ALMNATP53 | |
| SCHEMBL26597487 | 0.87 | NPSR1 (0.45) | MAPTNPSR1KMT2ALMNATP53 | |
| SCHEMBL20511717 | 0.86 | KMT2A (0.47) | MAPTNPSR1KMT2ALMNATP53 | |
| SCHEMBL29656495 | 0.86 | KMT2A (0.47) | MAPTNPSR1KMT2ALMNATP53 | |
| SCHEMBL30644688 | 0.85 | KMT2A (0.44) | MAPTNPSR1CNR1GPR35GPR55 | |
| SCHEMBL26597431 | 0.85 | KMT2A (0.44) | MAPTNPSR1CNR1GPR35GPR55 | |
| SCHEMBL29656407 | 0.84 | KMT2A (0.47) | MAPTNPSR1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601216-B1 | SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-25 | — | — | EP | disclosed |