Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.36 |
| ▸ | COASY | Q13057 | 1/20 | 0.35 |
| ▸ | DCAF1 | Q9Y4B6 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743169 | 1.00 | CTSA (0.39) | CTSAAURKAPARP1RPS6KB1AKT1 | |
| SCHEMBL20743906 | 0.90 | SOS1 (0.44) | CTSASOS1COASYPDE2APTGFR | |
| SCHEMBL20762257 | 0.90 | CTSA (0.39) | CTSASOS1COASYPDE2APTGFR | |
| SCHEMBL19283565 | 0.85 | GRIN1 (0.40) | CTSASOS1PTGFR | |
| SCHEMBL20762429 | 0.83 | CCNT1 (0.35) | CTSAPNMTSOS1COASYPDE2A | |
| SCHEMBL20743101 | 0.78 | SOS1 (0.46) | CTSAPARP1SOS1COASY | |
| SCHEMBL30645115 | 0.78 | SOS1 (0.46) | CTSAPARP1SOS1COASY | |
| SCHEMBL20743982 | 0.77 | CTSA (0.47) | CTSASOS1PTGFR | |
| SCHEMBL20744591 | 0.76 | SOS1 (0.40) | CTSASOS1PTGFR | |
| SCHEMBL20744168 | 0.75 | SOS1 (0.43) | CTSAPARP1SOS1COASY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | claimed |
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |