Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.43 |
| ▸ | CTSA | P10619 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | COASY | Q13057 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 5/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20744168 | 1.00 | SOS1 (0.43) | SOS1CTSAMAOBADORA2AADORA2B | |
| SCHEMBL30645115 | 0.90 | SOS1 (0.46) | SOS1CTSACOASYITGA5ITGB6 | |
| SCHEMBL20743101 | 0.90 | SOS1 (0.46) | SOS1CTSACOASYITGA5ITGB6 | |
| SCHEMBL20743145 | 0.86 | SOS1 (0.41) | SOS1CTSACOASYITGA5ITGB6 | |
| SCHEMBL30645123 | 0.86 | SOS1 (0.41) | SOS1CTSACOASYITGA5ITGB6 | |
| SCHEMBL20743039 | 0.86 | SOS1 (0.41) | SOS1ITGA5ITGB6ITGB8ALDH1A1 | |
| SCHEMBL30645040 | 0.86 | SOS1 (0.41) | SOS1ITGA5ITGB6ITGB8ALDH1A1 | |
| SCHEMBL20743761 | 0.86 | NPC1 (0.47) | SOS1ITGA5ITGB6ITGB8 | |
| SCHEMBL30645019 | 0.86 | NPC1 (0.47) | SOS1ITGA5ITGB6ITGB8 | |
| SCHEMBL20743906 | 0.85 | SOS1 (0.44) | SOS1CTSACOASY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |