Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.47 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743177 | 1.00 | ITGA5 (0.47) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL19284046 | 0.92 | ITGA5 (0.43) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL19283712 | 0.85 | MTOR (0.50) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL19283585 | 0.82 | MTOR (0.47) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL30645021 | 0.82 | ITGA5 (0.45) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL20744505 | 0.82 | ITGA5 (0.45) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL19283713 | 0.82 | ITGA5 (0.46) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL19283810 | 0.82 | KLRK1 (0.53) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL20743022 | 0.81 | KLRK1 (0.49) | ITGA5ITGB6ITGB8NPC1RAB9A | |
| SCHEMBL21821288 | 0.81 | KLRK1 (0.52) | ITGA5ITGB6ITGB8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |