Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339294 | 1.00 | EGFR (0.39) | EGFRLMNAHTTMAPTHPGD | |
| SCHEMBL16339959 | 0.87 | EGFR (0.38) | EGFRLMNAHTTMAPTHPGD | |
| SCHEMBL16339905 | 0.85 | EGFR (0.35) | EGFRLMNAHTTMAPTHPGD | |
| SCHEMBL16340201 | 0.84 | EGFR (0.45) | EGFRLMNAHTTMAPTHPGD | |
| SCHEMBL16339123 | 0.75 | KDM4E (0.35) | EGFRLMNAHTTHPGDKDM4E | |
| SCHEMBL498197 | 0.75 | ELANE (0.51) | HTTMAPTHPGDKDM4EPOLB | |
| SCHEMBL23562898 | 0.74 | CHRM4 (0.40) | KDM4EELANEF2PLAUALDH1A1 | |
| SCHEMBL22464668 | 0.74 | EGFR (0.39) | EGFRLMNAMAPTKDM4EPOLB | |
| SCHEMBL2260267 | 0.73 | ELANE (0.59) | HTTMAPTHPGDKDM4EPOLB | |
| SCHEMBL14895549 | 0.73 | MAPK1 (0.46) | LMNAMAPTHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116897150-A | Novel bifunctional molecules for protein-targeted degradation | 安菲斯塔治疗有限公司 | 2023-10-17 | — | — | CN | disclosed |