Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888170 | 0.85 | ATR (0.59) | ATRCYP17A1METAP1AAK1MAPKAPK2 | |
| SCHEMBL16992920 | 0.85 | ATR (0.46) | ATRCYP17A1METAP1KCNQ4KCNQ5 | |
| SCHEMBL31146037 | 0.83 | ATR (0.48) | ATRCYP17A1METAP1KCNQ4KCNQ5 | |
| SCHEMBL30153950 | 0.83 | ATR (0.44) | ATRCYP17A1METAP1KCNQ4KCNQ5 | |
| SCHEMBL29418624 | 0.83 | ATR (0.56) | ATRCYP17A1METAP1AAK1MAPKAPK2 | |
| SCHEMBL797495 | 0.83 | ATR (0.56) | ATRCYP17A1METAP1AAK1MAPKAPK2 | |
| SCHEMBL21605149 | 0.81 | ATR (0.48) | ATRCYP17A1METAP1AAK1MAPKAPK2 | |
| SCHEMBL30629673 | 0.81 | ATR (0.48) | ATRCYP17A1METAP1AAK1MAPKAPK2 | |
| SCHEMBL393203 | 0.79 | METAP1 (0.55) | ATRCYP17A1METAP1KCNQ4KCNQ5 | |
| SCHEMBL4393718 | 0.78 | ATR (0.58) | ATRCYP17A1METAP1AAK1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204308-A1 | OXAZEPINE DERIVATIVE | 帝人ファーマ株式会社 | 2023-10-26 | — | — | WO | disclosed |