Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.43 |
| ▸ | ULK1 | O75385 | 2/20 | 0.43 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25236840 | 1.00 | AURKA (0.49) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL1917337 | 0.84 | STK17A (0.60) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL3284454 | 0.82 | CDK1 (0.53) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL5562631 | 0.82 | AURKA (0.52) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL1916571 | 0.81 | GSK3A (0.56) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL578690 | 0.80 | GSK3A (0.56) | AURKAGSK3AGSK3BPTK2KDR | |
| SCHEMBL579089 | 0.80 | GSK3B (0.70) | AURKAGSK3AGSK3BPTK2JAK3 | |
| SCHEMBL4393743 | 0.80 | GSK3A (0.53) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL5567787 | 0.79 | MEN1 (0.48) | AURKASTK17AGSK3AGSK3BPTK2 | |
| SCHEMBL1491635 | 0.79 | AURKA (0.47) | AURKASTK17AGSK3AGSK3BPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043151-A | Pyrimidine or pyridine derivative and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-10 | — | — | CN | disclosed |