Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771216 | 1.00 | ESR1 (0.44) | ESR1RXRARXRBRXRGKDM4E | |
| SCHEMBL792502 | 0.93 | ESR1 (0.53) | ESR1RXRARXRBRXRG | |
| SCHEMBL792501 | 0.93 | ESR1 (0.53) | ESR1RXRARXRBRXRG | |
| SCHEMBL792503 | 0.93 | ESR1 (0.53) | ESR1RXRARXRBRXRG | |
| SCHEMBL792504 | 0.93 | ESR1 (0.53) | ESR1RXRARXRBRXRG | |
| SCHEMBL806206 | 0.89 | ESR1 (0.44) | ESR1RXRARXRBRXRGLMNA | |
| SCHEMBL30646350 | 0.89 | ESR1 (0.47) | ESR1RXRARXRBRXRGMGLL | |
| SCHEMBL770771 | 0.89 | ESR1 (0.47) | ESR1RXRARXRBRXRGMGLL | |
| SCHEMBL770766 | 0.89 | ESR1 (0.55) | ESR1RXRARXRBRXRGMGLL | |
| SCHEMBL806447 | 0.89 | ESR1 (0.43) | ESR1RXRARXRBRXRGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |