Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087765 | 1.00 | TACR1 (0.44) | TACR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29087762 | 1.00 | TACR1 (0.44) | TACR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29087738 | 0.95 | CHRM2 (0.46) | CHRM2CHRM5CHRM1CHRM3HIF1A | |
| SCHEMBL29087736 | 0.95 | CHRM2 (0.46) | CHRM2CHRM5CHRM1CHRM3HIF1A | |
| SCHEMBL29617639 | 0.95 | CHRM2 (0.46) | CHRM2CHRM5CHRM1CHRM3HIF1A | |
| SCHEMBL29087735 | 0.91 | PSEN1 (0.48) | CHRM2CHRM5CHRM1CHRM3HIF1A | |
| SCHEMBL30646794 | 0.91 | PSEN1 (0.48) | CHRM2CHRM5CHRM1CHRM3HIF1A | |
| SCHEMBL29087732 | 0.91 | PSEN1 (0.48) | CHRM2CHRM5CHRM1CHRM3HIF1A | |
| SCHEMBL29087681 | 0.91 | CHRM2 (0.52) | TACR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29087678 | 0.91 | CHRM2 (0.52) | TACR1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |