Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.74 |
| ▸ | BRD2 | P25440 | 1/20 | 0.74 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.74 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224139 | 1.00 | BRD4 (0.74) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL30647255 | 0.87 | BRD4 (0.74) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL29092601 | 0.87 | BRD4 (0.74) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL12411779 | 0.85 | BRD4 (1.00) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL29092673 | 0.85 | BRD4 (0.70) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL30647264 | 0.85 | BRD4 (0.70) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL30647190 | 0.84 | BRD4 (0.69) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL28223468 | 0.84 | BRD4 (0.69) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL28224136 | 0.81 | BRD4 (0.58) | BRD4BRD2BRD3BRDTKDM4E | |
| SCHEMBL18584654 | 0.81 | BRD4 (0.70) | BRD4BRD2BRD3BRDTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137542-B | Pyridone dicarboxamides as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-27 | — | — | CN | disclosed |