SCHEMBL30648124

SCHEMBL30648124

Oc1ccc([C@H](O)CN2C[C@H]3CC(Oc4ccc(F)cc4F)C[C@H]3C2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 20/20 1.00
GRIN2B Q13224 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29882969 1.00 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20983495 1.00 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL30648108 1.00 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20983494 1.00 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20086425 1.00 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20983525 0.89 GRIN1 (0.81) GRIN1GRIN2B
SCHEMBL17643347 0.89 GRIN1 (0.81) GRIN1GRIN2B
SCHEMBL29882765 0.89 GRIN1 (0.81) GRIN1GRIN2B
SCHEMBL30648129 0.89 GRIN1 (0.80) GRIN1GRIN2B
SCHEMBL30648116 0.89 GRIN1 (0.80) GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117120053-A Novel cyclopenta [ c ] pyrrole NR2B negative allosteric modulators 诺华股份有限公司 2023-11-24 CN claimed
CN-117120053-A Novel cyclopenta [ c ] pyrrole NR2B negative allosteric modulators 诺华股份有限公司 2023-11-24 CN disclosed