Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 1.00 |
| ▸ | PPARD | Q03181 | 6/20 | 1.00 |
| ▸ | PPARA | Q07869 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | FABP4 | P15090 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | NR4A2 | P43354 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | AKR1C3 | P42330 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875988 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Arachidonic Acid SCHEMBL18185463 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| SCHEMBL7875990 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| SCHEMBL17540736 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| SCHEMBL542242 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| SCHEMBL13033028 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Arachidonic Acid SCHEMBL25417373 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Arachidonic Acid SCHEMBL18185503 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Arachidonic Acid SCHEMBL607755 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Arachidonic Acid SCHEMBL20656587 | 1.00 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119559-A1 | Topically active agents to remove actinic keratoses and basal (BCC) and squamous (SCC) cell carcinomas using a combination of sulindac, its metabolites and derivatives with an oxidizing agent to generate reactive oxygen species nontoxic to normal cells; sulindac methionine sulfoxide/hydrogen peroxide | FLORIDA ATLANTIC UNIVERSITY (US) | 2008-05-22 | — | — | US | claimed |
| EP-1865972-A2 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2007-12-19 | — | — | EP | claimed |
| US-20060235080-A1 | Treatment or prevention of cancer and precancerous disorders | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-10-19 | — | — | US | claimed |
| WO-2006102439-A2 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-09-28 | — | — | WO | claimed |
| WO-2000044931-A2 | HIGH-THROUGHPUT SCREENING ASSAYS FOR MODULATORS OF ATPASE | BION, INC. (US) | 2000-08-03 | — | — | WO | claimed |
| US-4657856-A | FERMENTATION OF MUCOR, BLOCKING AGENTS, FLUORESCENT REAGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1987-04-14 | — | — | US | claimed |
| EP-0049078-B1 | GLUTATHIONE PEROXIDASE, PROCESS FOR PRODUCTION THEREOF, METHOD AND COMPOSITION FOR THE QUANTITATIVE DETERMINATION OF LIPID PEROXIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-04-30 | — | — | EP | claimed |
| EP-0049078-A2 | Glutathione peroxidase, process for production thereof, method and composition for the quantitative determination of lipid peroxide | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-04-07 | — | — | EP | claimed |
| US-20210041467-A1 | METHODS FOR ASSESSING THE NEED FOR AND THE EFFECTIVENESS OF THERAPY WITH ANTIOXIDANTS | THE PROIMMUNE COMPANY, LLC | 2021-02-11 | — | — | US | disclosed |
| US-20200141956-A1 | METHODS OF ASSESSING THE NEED FOR AND THE EFFECTIVENESS OF THERAPY WITH ANTIOXIDANTS | THE PROIMMUNE COMPANY, LLC | 2020-05-07 | — | — | US | disclosed |
| US-20160341748-A1 | Methods of assessing the need for and the effectiveness of therapy with antioxidants | CRUM ALBERT B (US) | 2016-11-24 | — | — | US | disclosed |
| US-9229014-B2 | Methods of assessing the need for and the effectiveness of therapy with antioxidants | THE PROIMMUNE COMPANY, LLC | 2016-01-05 | — | — | US | disclosed |
| US-8765808-B2 | Treatment or prevention of cancer and precancerous disorders | CHS PHARMA, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8603985-B2 | Treatment or prevention of cancer and precancerous disorders | CHS Pharma, Inc (US) | 2013-12-10 | — | — | US | disclosed |
| US-4900680-A | Method and apparatus for measuring lipid peroxide | TOHOKU ELECTRONIC INDUSTRIAL CO., LTD. (JP) | 1990-02-13 | — | — | US | disclosed |
| US-4657856-A | FERMENTATION OF MUCOR, BLOCKING AGENTS, FLUORESCENT REAGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0049078-B1 | GLUTATHIONE PEROXIDASE, PROCESS FOR PRODUCTION THEREOF, METHOD AND COMPOSITION FOR THE QUANTITATIVE DETERMINATION OF LIPID PEROXIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-04-30 | — | — | EP | disclosed |
| US-4464304-A | Vinyl Cyclopropyl compounds as precursors to fatty acid oxidation products | DUKE UNIVERSITY (US) | 1984-08-07 | — | — | US | disclosed |
| US-4350834-A | Vinyl cyclopropyl compounds as precursors to fatty acid oxidation products | DUKE UNIVERSITY (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0049078-A2 | Glutathione peroxidase, process for production thereof, method and composition for the quantitative determination of lipid peroxide | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |