Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH2 | Q9NR71 | 2/20 | 1.00 |
| ▸ | CETP | P11597 | 4/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506537 | 1.00 | ASAH2 (1.00) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL30145483 | 1.00 | ASAH2 (1.00) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL13849917 | 1.00 | ASAH2 (1.00) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL27013983 | 1.00 | ASAH2 (1.00) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL12252107 | 0.99 | ASAH2 (0.97) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL29967428 | 0.99 | ASAH2 (0.97) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL12227954 | 0.99 | ASAH2 (0.97) | ASAH2CETPTHRBMEN1KMT2A | |
| Sulfuric Acid SCHEMBL10522463 | 0.93 | ASAH2 (0.87) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL18506534 | 0.86 | ASAH2 (0.75) | ASAH2CETPTHRBMEN1KMT2A | |
| SCHEMBL3712347 | 0.85 | ASAH2 (0.74) | ASAH2CETPTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |