Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 5/20 | 0.63 |
| ▸ | CDK2 | P24941 | 5/20 | 0.63 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.63 |
| ▸ | EGFR | P00533 | 2/20 | 0.63 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117070 | 0.78 | KDM4E (0.42) | CCNA2CDK2CCNA1EGFRACHE | |
| SCHEMBL30656125 | 0.75 | KDM4E (0.58) | CHUKACHEBCHEALDH1A1KDM4E | |
| SCHEMBL10987690 | 0.73 | ADORA1 (0.46) | CCNA2CDK2CCNA1EGFRCHUK | |
| SCHEMBL13802923 | 0.72 | CCNA2 (0.47) | CCNA2CDK2CCNA1EGFRCHUK | |
| SCHEMBL27883168 | 0.72 | KDM4E (0.57) | ACHESMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL30656058 | 0.71 | ADORA1 (0.46) | CCNA2CDK2CCNA1EGFRADORA1 | |
| SCHEMBL7291890 | 0.71 | CYP1A2 (0.58) | CCNA2CDK2CCNA1EGFRSMN1; SMN2 | |
| SCHEMBL7282692 | 0.70 | SMN1; SMN2 (0.47) | CCNA2CDK2CCNA1EGFRSMN1; SMN2 | |
| SCHEMBL29477047 | 0.70 | CCNA2 (0.48) | CCNA2CDK2CCNA1EGFRCHUK | |
| SCHEMBL11701910 | 0.70 | ADORA1 (0.52) | CCNA2CDK2CCNA1EGFRCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |