SCHEMBL30656868

SCHEMBL30656868

Cn1c(=O)cnc2ccc(Cl)nc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 15/20 0.51
ALDH1A1 P00352 11/20 0.51
HSD17B10 Q99714 9/20 0.51
CASP1 P29466 8/20 0.51
CASP7 P55210 7/20 0.51
HPGD P15428 4/20 0.51
CYP2D6 P10635 3/20 0.51
USP2 O75604 8/20 0.49
CYP2C19 P33261 6/20 0.49
CYP3A4 P08684 6/20 0.49
TSHR P16473 4/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CYP2C9 P11712 3/20 0.49
MAPK1 P28482 2/20 0.49
GLA P06280 2/20 0.49
CLK4 Q9HAZ1 3/20 0.47
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
CCND2 P30279 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21429505 1.00 CYP1A2 (0.51) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL30828539 0.89 CYP1A2 (0.41) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL17813507 0.81 CYP1A2 (0.53) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL30194234 0.79 CYP1A2 (0.41) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL21428628 0.79 CYP1A2 (0.41) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL31532070 0.77 CYP1A2 (0.61) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL31532069 0.77 CYP1A2 (0.61) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL18544265 0.77 CYP1A2 (0.60) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL5364876 0.74 CDK4 (0.43) CYP1A2ALDH1A1HSD17B10CASP1CASP7
SCHEMBL4141389 0.73 CYP1A2 (0.36) CYP1A2ALDH1A1HSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117794939-A Antibiotic pyrazinothiazine derivatives and process for their preparation 巴格沃克斯研究印度私人有限公司 2024-03-29 CN disclosed
CN-112218862-B Oxazolidinone antibiotic compounds and process for preparing same 巴格沃克斯研究有限公司 2024-01-02 CN disclosed