Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809867 | 1.00 | MEN1 (0.68) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29690667 | 0.83 | HPGD (0.56) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28809878 | 0.83 | HPGD (0.56) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL980968 | 0.83 | MAPT (0.82) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6315596 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL30657206 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11693331 | 0.79 | RECQL (0.54) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL333699 | 0.78 | MAPT (0.61) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL333454 | 0.77 | MEN1 (0.74) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL333866 | 0.75 | MEN1 (0.59) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591215-B | N-substituted indole compounds and their use in the treatment of tuberculosis | 华东师范大学 | 2023-12-01 | — | — | CN | disclosed |