Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412655 | 1.00 | TNF (0.36) | TNFCYP11B1CYP11B2CLK1DYRK1A | |
| SCHEMBL26658374 | 0.83 | CYP3A4 (0.43) | CYP2A6CYP3A4HTTKDM4EGMNN | |
| SCHEMBL30180775 | 0.80 | TNF (0.46) | TNFCYP11B1CYP11B2CLK1DYRK1A | |
| SCHEMBL669865 | 0.80 | TNF (0.46) | TNFCYP11B1CYP11B2CLK1DYRK1A | |
| SCHEMBL16738368 | 0.79 | TNF (0.45) | TNFCYP11B1CYP11B2CLK1DYRK1A | |
| Hydrochloric Acid SCHEMBL19358949 | 0.79 | TNF (0.45) | TNFCYP11B1CYP11B2MAPK10HTT | |
| Bromide SCHEMBL16701359 | 0.79 | TNF (0.45) | TNFCYP11B1CYP11B2CLK1DYRK1A | |
| Hydrochloric Acid SCHEMBL1307572 | 0.79 | TNF (0.45) | TNFCYP11B1CYP11B2MAPK10HTT | |
| SCHEMBL5550507 | 0.79 | TNF (0.45) | TNFCYP11B1CYP11B2CLK1DYRK1A | |
| SCHEMBL15413082 | 0.78 | TNF (0.41) | TNFCYP11B1CYP11B2CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497715-A | Preparation and application of 7-aza-indeno isoquinoline | 珀杜研究基金会 | 2025-02-21 | — | — | CN | disclosed |
| CN-119497715-A | Preparation and application of 7-aza-indeno isoquinoline | 珀杜研究基金会 | 2025-02-21 | — | — | CN | disclosed |