Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 19/20 | 0.69 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22968944 | 1.00 | IL23R (0.69) | IL23RMAGI3 | |
| SCHEMBL22968949 | 0.98 | IL23R (0.67) | IL23RMAGI3 | |
| SCHEMBL22969044 | 0.94 | IL23R (0.65) | IL23RMAGI3 | |
| SCHEMBL30658152 | 0.94 | IL23R (0.65) | IL23RMAGI3 | |
| SCHEMBL26622449 | 0.94 | IL23R (0.66) | IL23RMAGI3 | |
| SCHEMBL22969246 | 0.94 | IL23R (0.66) | IL23R | |
| SCHEMBL30658140 | 0.94 | IL23R (0.66) | IL23R | |
| SCHEMBL30658133 | 0.93 | IL23R (0.72) | IL23R | |
| SCHEMBL22969247 | 0.91 | IL23R (0.68) | IL23R | |
| SCHEMBL22969242 | 0.91 | IL23R (0.67) | IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12496350-B2 | Cyclic peptidyl inhibitors of CAL-PDZ binding domain | OHIO STATE INNOVATION FOUNDATION (US) | 2025-12-16 | — | — | US | disclosed |
| US-20240173423-A1 | CYCLIC PEPTIDYL INHIBITORS OF CAL-PDZ BINDING DOMAIN | OHIO STATE INNOVATION FOUNDATION | 2024-05-30 | — | — | US | disclosed |
| US-11793884-B2 | Cyclic peptidyl inhibitors of CAL-PDZ binding domain | OHIO STATE INNOVATION FOUNDATION (US) | 2023-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793884-B2 | Cyclic peptidyl inhibitors of CAL-PDZ binding domain | CNBP, CALU, CLSPN | IL23R 4090/4885MAGI3 386/4885 |
| US-20240173423-A1 | CYCLIC PEPTIDYL INHIBITORS OF CAL-PDZ BINDING DOMAIN | CNBP, CALU, CLSPN | IL23R 4090/4885MAGI3 386/4885 |
| US-12496350-B2 | Cyclic peptidyl inhibitors of CAL-PDZ binding domain | CNBP, CALU, CLSPN | IL23R 4090/4885MAGI3 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.