SCHEMBL30658208

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CS)C(=O)O)[C@@H](C)O

nearest known ligand 0.74

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	15/20	0.72

▸	GCGR	P47871	8/20	0.70

▸	CCKBR	P32239	4/20	0.69

▸	CALCR	P30988	3/20	0.69

▸	KEAP1	Q14145	1/20	0.67

▸	GIPR	P48546	5/20	0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30658246	0.94	GLP1R (0.79)	GLP1RGCGRCALCRKEAP1GIPR
SCHEMBL31457381	0.94	GLP1R (0.72)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL30159330	0.93	CALCR (0.73)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL31217658	0.93	CALCR (0.75)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL30658237	0.93	CALCR (0.76)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL30771981	0.93	CALCR (0.77)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL30932077	0.92	CALCR (0.76)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL29706316	0.92	GLP1R (0.71)	GLP1RGCGRCCKBRCALCRGIPR
SCHEMBL31027131	0.92	CALCR (0.76)	GLP1RGCGRCCKBRCALCRKEAP1
SCHEMBL30437189	0.92	CALCR (0.74)	GLP1RGCGRCCKBRCALCRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11753627-B2	Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US)	2023-09-12	—	—	US	disclosed