SCHEMBL30659062

SCHEMBL30659062

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 20/20 0.75
BACE2 Q9Y5Z0 5/20 0.75
CTSD P07339 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506418 0.94 BACE1 (0.73) BACE1BACE2CTSD
SCHEMBL32667937 0.94 BACE1 (0.66) BACE1BACE2CTSD
SCHEMBL29350817 0.94 BACE1 (0.66) BACE1BACE2CTSD
SCHEMBL30198937 0.93 BACE1 (0.73) BACE1BACE2CTSD
SCHEMBL30258973 0.92 BACE1 (0.70) BACE1BACE2CTSD
SCHEMBL30804672 0.92 BACE1 (0.69) BACE1BACE2CTSD
SCHEMBL30099486 0.91 BACE1 (0.69) BACE1BACE2CTSD
SCHEMBL29499677 0.90 BACE1 (0.68) BACE1BACE2CTSD
SCHEMBL30905993 0.89 BACE1 (0.61) BACE1BACE2CTSD
SCHEMBL30903463 0.89 BACE1 (0.67) BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025128693-A1 AN ENGINEERED MAMMALIAN NUCLEASE FOR IMPROVED MAPPING OF 3-D GENOME ARCHITECTURE FROM NUCLEOSOME TO CHROMOSOME SCALE THE ROCKEFELLER UNIVERSITY (US) 2025-06-19 WO disclosed
WO-2023227913-A1 CREATING NUCLEIC ACIDS FOR IN-VITRO PROTEIN SYNTHESIS NUCLERA LTD (GB) 2023-11-30 WO disclosed