Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26955595 | 1.00 | CRBN (0.51) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL30659336 | 1.00 | CRBN (0.51) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL30659327 | 1.00 | CRBN (0.51) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL26930519 | 1.00 | CRBN (0.51) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL30659378 | 1.00 | CRBN (0.51) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL26930906 | 0.95 | CRBN (0.52) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL26930734 | 0.95 | CRBN (0.52) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL30796994 | 0.95 | CRBN (0.52) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL27453593 | 0.95 | CRBN (0.52) | CRBNDDB1MAPTKDM4ETHRB | |
| SCHEMBL30659493 | 0.88 | CRBN (0.51) | CRBNDDB1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536656-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239750-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |