Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094715 | 0.83 | GLA (1.00) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL1104933 | 0.80 | GLA (0.72) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL240958 | 0.80 | GLA (1.00) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL11149402 | 0.77 | GLA (0.81) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL1104929 | 0.77 | GLA (0.76) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL28373300 | 0.77 | SLC16A3 (0.69) | GLACA9KDM4EMAOBCA12 | |
| SCHEMBL30659716 | 0.77 | CA12 (0.63) | GLAKMT2ACA9KDM4EMAOB | |
| SCHEMBL1460890 | 0.77 | GLA (0.68) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL8835330 | 0.76 | GLA (0.67) | GLAMEN1KMT2ACA9MIF | |
| SCHEMBL11501433 | 0.75 | GLA (0.77) | GLAMEN1KMT2ACA9MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057850-B | Aloe-emodin derivative and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2023-11-10 | — | — | CN | disclosed |