Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 10/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276698 | 1.00 | MAPT (0.51) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29276690 | 0.79 | SCN9A (0.36) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL15520763 | 0.75 | MAPT (0.67) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL14699380 | 0.74 | MEN1 (0.60) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL30660614 | 0.74 | MAPT (0.50) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL30660594 | 0.74 | HDAC3 (0.60) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL21493036 | 0.73 | KLKB1 (0.38) | MAPTLMNAALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL30744550 | 0.73 | KLKB1 (0.38) | MAPTLMNAALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL30697176 | 0.73 | MAPT (0.49) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3593783 | 0.72 | MAPT (0.68) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236960-A1 | CARBOXAMIDE DERIVATIVE HAVING RSK INHIBITORY EFFECT, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 上海科恩泰生物医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |