Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | BCR | P11274 | 3/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
| ▸ | WEE1 | P30291 | 1/20 | 0.47 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.47 |
| ▸ | ABL2 | P42684 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21836257 | 1.00 | MAPK14 (0.47) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836258 | 1.00 | MAPK14 (0.47) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836207 | 0.89 | BRAF (0.45) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836208 | 0.89 | BRAF (0.45) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL29320024 | 0.85 | ABL1 (0.51) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836270 | 0.83 | BRAF (0.46) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836267 | 0.83 | BRAF (0.46) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836214 | 0.83 | BRAF (0.46) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL21836213 | 0.83 | BRAF (0.46) | MAPK14ABL1BCRBRAFEPHB6 | |
| SCHEMBL30664376 | 0.83 | BRAF (0.46) | MAPK14ABL1BCRBRAFEPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447464-A | Method for producing optically active compound | 首日生物制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-111032047-B | Method for producing optically active compound | 多特疗法-1公司 | 2023-10-27 | — | — | CN | disclosed |