SCHEMBL30665444

SCHEMBL30665444

CC(=O)c1cc(C[C@H](N)C(=O)OCc2ccccc2)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.49
MAOB P27338 3/20 0.48
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
EGFR P00533 1/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
ALOX15 P16050 1/20 0.47
PTGS1 P23219 1/20 0.47
HTR2A P28223 1/20 0.47
PTGS2 P35354 1/20 0.47
RECQL P46063 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TYR P14679 3/20 0.45
ALDH1A1 P00352 1/20 0.45
MAOA P21397 2/20 0.45
HNF4A P41235 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070495 0.87 SLC7A5 (0.63) SLC7A5TDP1KDM4EUSP2EGFR
SCHEMBL11440820 0.87 SLC7A5 (0.63) SLC7A5TDP1KDM4EUSP2EGFR
SCHEMBL31453291 0.87 SLC7A5 (0.63) SLC7A5TDP1KDM4EUSP2EGFR
SCHEMBL27406548 0.86 SLC7A5 (0.50) SLC7A5TDP1KDM4EUSP2EGFR
SCHEMBL14617681 0.86 SLC7A5 (0.48) SLC7A5TDP1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL4126484 0.85 SLC7A5 (0.61) SLC7A5TDP1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL4188588 0.85 SLC7A5 (0.61) SLC7A5TDP1KDM4EUSP2EGFR
SCHEMBL27544345 0.84 SLC7A5 (0.48) SLC7A5MAOBTDP1KDM4EUSP2
SCHEMBL5207230 0.84 SLC7A5 (0.48) SLC7A5MAOBTDP1KDM4EUSP2
SCHEMBL5369259 0.84 CA12 (0.54) SLC7A5TDP1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947858-A Compounds selectively inhibiting four amino acid modifications of ADP, preparation and application thereof 首都医科大学 2023-10-27 CN disclosed