Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199220 | 0.88 | ESR2 (0.63) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL17462462 | 0.88 | ESR2 (0.63) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL31158935 | 0.86 | HDAC1 (0.44) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL30666328 | 0.85 | USP30 (0.45) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL29124891 | 0.84 | ESR2 (0.42) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL30666315 | 0.84 | ESR2 (0.42) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL30335960 | 0.83 | ESR2 (0.53) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL28970117 | 0.83 | ESR2 (0.53) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL38653272 | 0.83 | ESR2 (0.41) | ESR2NR1H2MAPK1DDB1CRBN | |
| SCHEMBL38652784 | 0.82 | DDB1 (0.48) | ESR2NR1H2MAPK1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203194-A | Novel compounds useful as STING agonists and uses thereof | 北京加科思新药研发有限公司 | 2023-12-08 | — | — | CN | disclosed |