Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 17/20 | 0.59 |
| ▸ | RPS6KA2 | Q15349 | 3/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.51 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.51 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30668143 | 1.00 | RPS6KA3 (0.59) | RPS6KA3RPS6KA2MAPKAPK2RPS6KA1RPS6KA6 | |
| SCHEMBL30668153 | 0.91 | RPS6KA3 (0.62) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30668189 | 0.90 | RPS6KA3 (0.66) | RPS6KA3RPS6KA2MAPKAPK2RPS6KA1RPS6KA6 | |
| SCHEMBL30668154 | 0.90 | RPS6KA3 (0.66) | RPS6KA3RPS6KA2MAPKAPK2RPS6KA1RPS6KA6 | |
| SCHEMBL30668171 | 0.89 | RPS6KA3 (0.60) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30668174 | 0.89 | RPS6KA3 (0.60) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30668183 | 0.84 | RPS6KA3 (0.66) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30668158 | 0.84 | RPS6KA3 (0.66) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30668128 | 0.79 | RPS6KA3 (0.60) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1983889 | 0.72 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186097-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |