Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | KDM6A | O15550 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669409 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669359 | 0.88 | KDM4E (0.49) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669374 | 0.88 | KDM4E (0.49) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669367 | 0.84 | CYP2D6 (0.49) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669341 | 0.84 | KDM4E (0.49) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669377 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669388 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669331 | 0.84 | KDM4E (0.46) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669350 | 0.84 | KDM4E (0.46) | SMN1; SMN2KDM4ETP53CYP2D6HTT | |
| SCHEMBL30669330 | 0.83 | MAOB (0.47) | SMN1; SMN2KDM4ETP53CYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105853-A | 3-hydroxypyridine-4 (H) -ketone derivative, and preparation method and application thereof | 浙江工业大学 | 2023-11-24 | — | — | CN | disclosed |