Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | HCK | P08631 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.47 |
| ▸ | PRKDC | P78527 | 2/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17847214 | 1.00 | PIK3CA (0.47) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL15091426 | 0.85 | PIK3CA (0.46) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL17336535 | 0.85 | PIK3CA (0.48) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL1396849 | 0.85 | PIK3CD (0.48) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL30918924 | 0.84 | PIK3CA (0.45) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL15091891 | 0.84 | PIK3CA (0.45) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL26498723 | 0.84 | PIK3CA (0.45) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL17583735 | 0.84 | PIK3CA (0.45) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL17859395 | 0.84 | PIK3CB (0.45) | PIK3CAPIK3CDABL1EGFRHCK | |
| SCHEMBL21920779 | 0.82 | PIK3CD (0.44) | PIK3CAPIK3CDABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981670-A | Polycyclic compound containing nitrogen heterocycle, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |