SCHEMBL30670481

SCHEMBL30670481

O=C(O)N1C[C@@H]2CCN(C(=O)c3cc(F)ccc3-n3nccn3)C[C@@H]2C1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.63
HCRTR2 O43614 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27030132 1.00 HCRTR1 (0.63) HCRTR1HCRTR2
SCHEMBL27029804 0.86 HCRTR1 (0.66) HCRTR1HCRTR2
SCHEMBL29930931 0.86 HCRTR1 (0.62) HCRTR1HCRTR2
SCHEMBL27030146 0.86 HCRTR1 (0.62) HCRTR1HCRTR2
SCHEMBL27029913 0.86 HCRTR1 (0.62) HCRTR1HCRTR2
SCHEMBL27029984 0.85 HCRTR1 (0.87) HCRTR1HCRTR2
SCHEMBL27274548 0.85 HCRTR1 (0.59) HCRTR1HCRTR2
SCHEMBL27029858 0.85 HCRTR1 (0.87) HCRTR1HCRTR2
SCHEMBL30670443 0.85 HCRTR1 (0.59) HCRTR1HCRTR2
SCHEMBL1671780 0.83 HCRTR1 (0.61) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116981670-A Polycyclic compound containing nitrogen heterocycle, preparation method and application thereof 上海翰森生物医药科技有限公司 2023-10-31 CN disclosed