Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | AURKA | O14965 | 3/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946 | 1.00 | PIK3CD (0.49) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL30670914 | 0.95 | PIK3CD (0.55) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL8975 | 0.95 | PIK3CD (0.55) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL30670869 | 0.94 | PIK3CD (0.44) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL8721 | 0.94 | PIK3CD (0.44) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL15688348 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL8573 | 0.86 | PIK3CD (0.54) | PIK3CDPIK3CGMAP4K4MAPK14GABRP | |
| SCHEMBL16783465 | 0.85 | PIK3CD (0.45) | PIK3CDPIK3CGMAP4K4AURKAAURKB | |
| SCHEMBL8546 | 0.84 | PIK3CD (0.43) | PIK3CDPIK3CGAURKAMAPK14MEN1 | |
| SCHEMBL16395748 | 0.84 | PIK3CD (0.53) | PIK3CDPIK3CGMAP4K4MAPK14GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | disclosed |