Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574 | 1.00 | PIK3CD (0.58) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL30013890 | 0.95 | PIK3CD (0.57) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL8769 | 0.95 | PIK3CD (0.57) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL8841 | 0.93 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL29651599 | 0.93 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL8116 | 0.91 | PIK3CD (0.50) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL30670805 | 0.91 | PIK3CD (0.50) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL8597 | 0.90 | PIK3CD (0.53) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL30670872 | 0.90 | PIK3CD (0.53) | PIK3CDPIK3R1PIK3CGCSNK1EPIK3R2 | |
| SCHEMBL8633 | 0.90 | PIK3CD (0.52) | PIK3CDPIK3R1PIK3CGPIK3R2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4292596-A1 | METHOD AND COMBINATION FOR TREATING TUMORS | Curon Biopharmaceutical (Shanghai) Co., Limited (CN) | 2023-12-20 | — | — | EP | claimed |
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | claimed |
| EP-4292596-A1 | METHOD AND COMBINATION FOR TREATING TUMORS | Curon Biopharmaceutical (Shanghai) Co., Limited (CN) | 2023-12-20 | — | — | EP | disclosed |
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | disclosed |