Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274 | 1.00 | PIK3CD (0.43) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL30670844 | 0.94 | ADORA2A (0.44) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL8877 | 0.94 | ADORA2A (0.44) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL7838 | 0.92 | PIK3CD (0.51) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL30013385 | 0.92 | PIK3CD (0.51) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL9178 | 0.90 | PIK3CD (0.49) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL30013632 | 0.90 | PIK3CD (0.49) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL8478 | 0.89 | ADORA2A (0.41) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL30670818 | 0.89 | ADORA2A (0.41) | PIK3CDADORA2AADORA2BADORA1PIK3R1 | |
| SCHEMBL30670805 | 0.88 | PIK3CD (0.50) | PIK3CDADORA2AADORA2BADORA1PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | disclosed |