Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.68 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26966647 | 1.00 | CHRM1 (0.68) | CHRM1IRAK1CYP11B1CYP11B2 | |
| SCHEMBL30671916 | 0.88 | CHRM1 (0.55) | CHRM1CYP11B1CYP11B2 | |
| SCHEMBL26966605 | 0.88 | CHRM1 (0.55) | CHRM1CYP11B1CYP11B2 | |
| SCHEMBL30671872 | 0.88 | CHRM1 (0.54) | CHRM1CYP11B1CYP11B2 | |
| SCHEMBL26966571 | 0.88 | CHRM1 (0.54) | CHRM1CYP11B1CYP11B2 | |
| SCHEMBL30671868 | 0.85 | CHRM1 (0.70) | CHRM1 | |
| SCHEMBL26966576 | 0.85 | CHRM1 (0.70) | CHRM1 | |
| SCHEMBL30671909 | 0.85 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL30671915 | 0.85 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL26966602 | 0.85 | CHRM1 (0.61) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851406-B2 | Positive allosteric modulators of the muscarinic acetylcholine receptor M1 | VANDERBILT UNIVERSITY (US) | 2023-12-26 | — | — | US | claimed |
| US-11851406-B2 | Positive allosteric modulators of the muscarinic acetylcholine receptor M1 | VANDERBILT UNIVERSITY (US) | 2023-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851406-B2 | Positive allosteric modulators of the muscarinic acetylcholine receptor M1 | CHRM1, CHRM2, CHRM4 | CHRM1 1/4885IRAK1 1008/4885CYP11B1 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.