Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 10/20 | 0.82 |
| ▸ | TYRO3 | Q06418 | 12/20 | 0.67 |
| ▸ | AXL | P30530 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377605 | 0.91 | MERTK (1.00) | MERTKTYRO3AXL | |
| SCHEMBL30672037 | 0.90 | TYRO3 (0.82) | MERTKTYRO3AXL | |
| SCHEMBL29626188 | 0.89 | MERTK (0.72) | MERTKTYRO3AXL | |
| SCHEMBL30672034 | 0.85 | MERTK (0.82) | MERTKTYRO3AXL | |
| SCHEMBL19377604 | 0.85 | MERTK (1.00) | MERTKTYRO3AXL | |
| SCHEMBL19377727 | 0.83 | MERTK (0.88) | MERTKTYRO3AXL | |
| SCHEMBL26613641 | 0.83 | MERTK (0.72) | MERTKTYRO3AXL | |
| SCHEMBL19377712 | 0.83 | MERTK (0.72) | MERTKTYRO3AXL | |
| SCHEMBL29626154 | 0.83 | MERTK (0.73) | MERTKTYRO3AXL | |
| SCHEMBL29626265 | 0.81 | TYRO3 (0.71) | MERTKTYRO3AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436461-B1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORP (US) | 2023-11-01 | — | — | EP | claimed |