Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18150794 | 1.00 | AKT1 (0.30) | AKT1 | |
| SCHEMBL29795027 | 0.91 | TNF (0.32) | — | |
| SCHEMBL18150907 | 0.91 | TNF (0.32) | — | |
| SCHEMBL20313903 | 0.87 | AKT1 (0.31) | AKT1 | |
| SCHEMBL18151249 | 0.85 | AKT1 (0.30) | AKT1 | |
| SCHEMBL38651802 | 0.85 | — | — | |
| SCHEMBL18151312 | 0.83 | PIK3CA (0.35) | AKT1 | |
| SCHEMBL29795035 | 0.83 | PIK3CA (0.35) | AKT1 | |
| SCHEMBL29794949 | 0.80 | AKT1 (0.33) | AKT1 | |
| SCHEMBL18159853 | 0.80 | TNF (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4493221-A2 | TARGETED BIFUNCTIONAL DEGRADERS | Yale University (US) | 2025-01-22 | — | — | EP | disclosed |
| CN-119212727-A | Targeted bifunctional degradants | 耶鲁大学 | 2024-12-27 | — | — | CN | disclosed |
| WO-2024182772-A2 | MANNOSE 6-PHOSPHATE RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| WO-2023178199-A2 | TARGETED BIFUNCTIONAL DEGRADERS | YALE UNIVERSITY (US) | 2023-09-21 | — | — | WO | disclosed |