SCHEMBL30673515

SCHEMBL30673515

CC(O)COc1nsnc1N1CCOCC1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.67
ADRB2 P07550 1/20 0.67
ADRB1 P08588 1/20 0.67
CYP3A4 P08684 1/20 0.67
HTR1A P08908 1/20 0.67
CYP2D6 P10635 1/20 0.67
ADRB3 P13945 1/20 0.67
NFKB1 P19838 1/20 0.67
DRD1 P21728 1/20 0.67
SIGMAR1 Q99720 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
KMT2A Q03164 4/20 0.60
HTT P42858 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
ALDH1A1 P00352 5/20 0.58
ALOX15 P16050 2/20 0.58
HSD17B10 Q99714 2/20 0.58
HPGD P15428 2/20 0.58
MAPT P10636 2/20 0.58
KDM4E B2RXH2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL7769369 0.91 SMN1; SMN2 (0.71) CYP1A2ADRB2ADRB1CYP3A4HTR1A
Maleic Acid SCHEMBL7769362 0.91 SMN1; SMN2 (0.71) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL18908562 0.86 CYP1A2 (0.71) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL11528671 0.85 TDP1 (0.69) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL11755634 0.84 CYP1A2 (0.74) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL11193337 0.84 CYP1A2 (0.74) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL10983705 0.84 CYP1A2 (0.74) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL1587314 0.84 CYP1A2 (0.67) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL10749123 0.84 TDP1 (0.67) CYP1A2ADRB2ADRB1CYP3A4HTR1A
SCHEMBL12648664 0.84 TDP1 (0.67) CYP1A2ADRB2ADRB1CYP3A4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023221852-A1 COMPOUND PHARMACEUTICAL COMPOSITION FOR TREATING GLAUCOMA AND USE THEREOF 沈阳药科大学 2023-11-23 WO claimed
CN-117466835-A Preparation method of 3-thiotimolol maleate 承德医学院 2024-01-30 CN disclosed