Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 14/20 | 0.60 |
| ▸ | FLT3 | P36888 | 4/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | KIT | P10721 | 1/20 | 0.59 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16049246 | 1.00 | CSF1R (0.60) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16047987 | 0.88 | CSF1R (0.57) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16046362 | 0.86 | CSF1R (0.67) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16046026 | 0.86 | CSF1R (0.67) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL21824009 | 0.84 | CSF1R (0.58) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16047906 | 0.84 | CSF1R (0.69) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16048363 | 0.84 | CSF1R (0.59) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16046256 | 0.84 | CSF1R (0.69) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16046249 | 0.84 | CSF1R (0.70) | CSF1RPDGFRAFLT3PDGFRBKDR | |
| SCHEMBL16046296 | 0.84 | CSF1R (0.68) | CSF1RPDGFRAFLT3PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632906-B1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO LTD (CN) | 2023-12-13 | — | — | EP | disclosed |