Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.47 |
| ▸ | MTOR | P42345 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 9/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961117 | 0.84 | PIK3CA (0.54) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL20049724 | 0.82 | PIK3CA (0.46) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL5019512 | 0.81 | PIK3CA (0.71) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL15354458 | 0.81 | CDK2 (0.57) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL17822227 | 0.79 | FLT3 (0.56) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL240522 | 0.79 | ADORA2A (0.50) | PIK3CAMTORPIK3R1 | |
| SCHEMBL15679247 | 0.79 | PIK3CA (0.58) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL9924586 | 0.79 | PIK3CA (0.58) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL12187039 | 0.79 | PIK3CA (0.58) | PIK3CAMTORGAAKDM4EALDH1A1 | |
| SCHEMBL27408140 | 0.79 | PIK3CA (0.58) | PIK3CAMTORGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |