Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | PCLAF | Q15004 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400726 | 1.00 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL28400721 | 1.00 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL28397302 | 0.99 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL30678594 | 0.99 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL28406574 | 0.99 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL29114339 | 0.99 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL30678591 | 0.99 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL28406570 | 0.99 | CRBN (0.63) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL28398837 | 0.98 | CRBN (0.64) | CRBNESR1HDAC1HDAC3HDAC2 | |
| SCHEMBL28398840 | 0.98 | CRBN (0.64) | CRBNESR1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205282-B | ER protein modulators and uses thereof | 上海科技大学 | 2023-12-01 | — | — | CN | disclosed |