Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL3157621 | 1.00 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| SCHEMBL30679046 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| Potassium Ion SCHEMBL30679053 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| Silver SCHEMBL4383778 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| Zinc Ion SCHEMBL1863860 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| SCHEMBL3147532 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| SCHEMBL1584746 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| SCHEMBL29377579 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| Potassium Ion SCHEMBL3152587 | 0.95 | TSHR (0.41) | TSHRACHEKEAP1NFE2L2HSD17B10 | |
| Water SCHEMBL7135005 | 0.93 | TSHR (0.39) | TSHRACHEKEAP1NFE2L2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513016-B | Sulfur-containing polymerizable monomer and use thereof | 尚美德齿科材料有限公司 | 2023-12-19 | — | — | CN | disclosed |