Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 17/20 | 0.79 |
| ▸ | BCL2 | P10415 | 3/20 | 0.79 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.79 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | BAD | Q92934 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15622240 | 0.92 | MCL1 (0.71) | MCL1BCL2BCL2L1ALBBAD | |
| SCHEMBL22436900 | 0.92 | MCL1 (0.66) | MCL1BCL2BCL2L1ALBALOX15 | |
| SCHEMBL15622375 | 0.90 | MCL1 (0.70) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL2202505 | 0.89 | MCL1 (0.76) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL30679056 | 0.89 | MCL1 (0.76) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL15622456 | 0.89 | MCL1 (0.71) | MCL1BCL2BCL2L1ALOX15 | |
| SCHEMBL2204455 | 0.89 | MCL1 (0.71) | MCL1BCL2BCL2L1ALB | |
| SCHEMBL29928296 | 0.88 | MCL1 (1.00) | MCL1BCL2BCL2L1ALBBAD | |
| SCHEMBL15622726 | 0.87 | MCL1 (0.71) | MCL1BCL2BCL2L1ALOX15 | |
| SCHEMBL15622777 | 0.86 | MCL1 (0.73) | MCL1BCL2BCL2L1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757884-B | Substituted macrocyclic indole derivatives | 拜耳股份公司 | 2023-12-19 | — | — | CN | disclosed |