SCHEMBL30679138

SCHEMBL30679138

N#Cc1ccnc(-c2ccc(Cc3cc(C(=O)N[C@H]4CCCC[C@@H]4O)nn4cccc34)cc2)c1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 19/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22322550 1.00 CHRM1 (0.75) CHRM1
SCHEMBL22322798 0.89 CHRM1 (0.81) CHRM1
SCHEMBL30679136 0.88 CHRM1 (0.80) CHRM1
SCHEMBL22322423 0.88 CHRM1 (0.80) CHRM1
SCHEMBL30435826 0.88 CHRM1 (0.75) CHRM1
SCHEMBL22322437 0.88 CHRM1 (0.75) CHRM1
SCHEMBL22322412 0.87 CHRM1 (0.73) CHRM1
SCHEMBL22322415 0.85 CHRM1 (1.00) CHRM1
SCHEMBL23972154 0.85 CHRM1 (0.84) CHRM1
SCHEMBL22322425 0.84 CHRM1 (0.68) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166160-B Pyrrolopyridazine derivatives as modulators of the positive allosteric of the muscarinic M1 receptor 苏文生命科学有限公司 2023-12-19 CN disclosed