Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | ADA | P00813 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948793 | 1.00 | ADORA2A (0.58) | ADORA2ALMNATP53NT5ECYP2C19 | |
| SCHEMBL29148198 | 1.00 | ADORA2A (0.58) | ADORA2ALMNATP53NT5ECYP2C19 | |
| SCHEMBL11896637 | 1.00 | ADORA2A (0.58) | ADORA2ALMNATP53NT5ECYP2C19 | |
| SCHEMBL29148201 | 1.00 | ADORA2A (0.58) | ADORA2ALMNATP53NT5ECYP2C19 | |
| SCHEMBL15679246 | 1.00 | ADORA2A (0.58) | ADORA2ALMNATP53NT5ECYP2C19 | |
| SCHEMBL12849772 | 0.89 | ADORA2A (0.62) | ADORA2ALMNANT5ECYP2C19ADORA3 | |
| SCHEMBL18061789 | 0.89 | ADORA2A (0.62) | ADORA2ALMNANT5ECYP2C19ADORA3 | |
| SCHEMBL465589 | 0.89 | ADORA2A (0.62) | ADORA2ALMNANT5ECYP2C19ADORA3 | |
| SCHEMBL20991001 | 0.89 | ADORA2A (0.62) | ADORA2ALMNANT5ECYP2C19ADORA3 | |
| SCHEMBL465590 | 0.89 | ADORA2A (0.62) | ADORA2ALMNANT5ECYP2C19ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209980-B | substituted purine nucleotides | 阿堤亚制药公司 | 2023-12-05 | — | — | CN | disclosed |