Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24772750 | 1.00 | MAP4K4 (0.47) | MAP4K4KITHDAC2HDAC1CYP11B2 | |
| SCHEMBL30406162 | 0.78 | KIT (0.52) | MAP4K4KITCYP11B2SCD5JAK3 | |
| SCHEMBL30456119 | 0.77 | KIT (0.49) | KITCYP11B2SCD5JAK3CYP3A4 | |
| SCHEMBL15728505 | 0.76 | MAP4K4 (0.61) | MAP4K4KITADKALDH1A1SMARCA2 | |
| SCHEMBL30405762 | 0.75 | HTT (0.49) | MAP4K4KITHDAC2HDAC1CYP11B2 | |
| SCHEMBL25422069 | 0.75 | HTT (0.49) | MAP4K4KITHDAC2HDAC1CYP11B2 | |
| SCHEMBL25270429 | 0.75 | KIT (0.45) | KITHDAC2HDAC1CYP11B2ACACB | |
| SCHEMBL31579068 | 0.74 | MAP4K4 (0.43) | MAP4K4KITHDAC2HDAC1CYP11B2 | |
| SCHEMBL18291310 | 0.74 | CYP3A4 (0.47) | HDAC2HDAC1CYP11B2ACACBSCD5 | |
| SCHEMBL30664043 | 0.74 | CYP3A4 (0.47) | HDAC2HDAC1CYP11B2ACACBSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222640-A | Heterocyclic compounds as FGFR inhibitors and uses thereof | 先声再明医药有限公司 | 2023-12-12 | — | — | CN | disclosed |