⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536086 | 0.83 | — | — | |
| SCHEMBL270795 | 0.73 | — | — | |
| SCHEMBL8165837 | 0.73 | — | — | |
| SCHEMBL5467094 | 0.71 | — | — | |
| SCHEMBL9190329 | 0.69 | TSHR (0.44) | — | |
| SCHEMBL10002731 | 0.69 | — | — | |
| SCHEMBL1880750 | 0.67 | — | — | |
| SCHEMBL5674715 | 0.65 | — | — | |
| SCHEMBL23714611 | 0.65 | TSHR (0.40) | — | |
| SCHEMBL4340727 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150112061-A1 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN | PURDUE RESEARCH FOUNDATION (US) | 2015-04-23 | — | — | US | claimed |
| US-8946220-B2 | Compositions and uses thereof to ameliorate pain | PURDUE RESEARCH FOUNDATION (US) | 2015-02-03 | — | — | US | claimed |
| US-20130345424-A1 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN | PURDUE RESEARCH FOUNDATION (US) | 2013-12-26 | — | — | US | claimed |
| WO-2012119045-A2 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN | PURDUE RESEARCH FOUNDATION (US) | 2012-09-07 | — | — | WO | claimed |
| US-20100267718-A1 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them | HIMMELSBACH FRANK | 2010-10-21 | — | — | US | claimed |
| US-20060264450-A1 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them | HIMMELSBACH FRANK | 2006-11-23 | — | — | US | claimed |
| EP-1641767-A2 | BICYCLIC HETEROCYCLES, DRUGS CONTAINING SAID COMPOUNDS, THE USE THEREOF AND METHOD FOR PREPARING THE SAME | Boehringer Ingelheim International GmbH (DE) | 2006-04-05 | — | — | EP | claimed |
| US-20050014772-A1 | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | claimed |
| WO-2004108664-A2 | BICYCLIC HETEROCYCLES, DRUGS CONTAINING SAID COMPOUNDS, THE USE THEREOF AND METHOD FOR PREPARING THE SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-16 | — | — | WO | claimed |
| US-20170065584-A1 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN | PURDUE RESEARCH FOUNDATION (US) | 2017-03-09 | — | — | US | disclosed |
| US-9498477-B2 | Compositions and uses thereof to ameliorate pain | PURDUE RESEARCH FOUNDATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150112061-A1 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN | PURDUE RESEARCH FOUNDATION (US) | 2015-04-23 | — | — | US | disclosed |
| US-8946220-B2 | Compositions and uses thereof to ameliorate pain | PURDUE RESEARCH FOUNDATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20130345424-A1 | COMPOSITIONS AND USES THEREOF TO AMELIORATE PAIN | PURDUE RESEARCH FOUNDATION (US) | 2013-12-26 | — | — | US | disclosed |
| US-5011623-A | Nonlinear optical material and nonlinear optical device | CANON KABUSHIKI KAISHA (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4981614-A | COMPRISING A MIXTURE OF POLYLACTONE OR NYLON COPOLYMER AND AN ORGANIC GUEST ELECTRONEGATIVE COMPOUND; NONLINEAR OPTICAL DEVICES; FILMS FOR DISPLAYS; CRYSTAL WAVELENGTH CONVERTERS FOR LASERS | CANON KABUSHIKI KAISHA (JP) | 1991-01-01 | — | — | US | disclosed |
| US-4946261-A | Recording method and recording apparatus | CANON KABUSHIKI KAISHA (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0332455-A2 | Photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0295145-A2 | Recording method and recording apparatus | CANON KABUSHIKI KAISHA (JP) | 1988-12-14 | — | — | EP | disclosed |
| EP-0284229-A1 | Nonlinear optical material and method for orientation thereof | CANON KABUSHIKI KAISHA (JP) | 1988-09-28 | — | — | EP | disclosed |