Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
| ▸ | PIK3R5 | Q8WYR1 | 3/20 | 0.31 |
| ▸ | PIK3R3 | Q92569 | 3/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17382050 | 1.00 | GRM5 (0.33) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17382140 | 0.96 | PIK3CD (0.33) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL20731124 | 0.95 | GRM5 (0.32) | GRM5 | |
| SCHEMBL30681691 | 0.95 | GRM5 (0.32) | GRM5 | |
| SCHEMBL31236958 | 0.95 | GRM5 (0.33) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17381989 | 0.94 | GRM5 (0.34) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17381644 | 0.93 | PIK3CD (0.35) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17381965 | 0.93 | GRM5 (0.32) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17381587 | 0.93 | GRM5 (0.32) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17381953 | 0.92 | PIK3CD (0.35) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157929-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | ARES TRADING SA (CH) | 2023-12-13 | — | — | EP | disclosed |